Structural biology

Membrane proteins: structure, function and drug design

Stereo view of the complex showing the GGA1 VHS domain as a ribbon diagram

Membrane proteins perform important biological activities to transfer materials and information into and out of a cell. They are also important as targets for drug design. Crystallization of membrane proteins is difficult and in many cases only a very small crystals are formed. Development of high-brilliant light source and higher sensitivity detectors allows the structural analysis of micro-crystals.

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構造生物学研究センターStructual Biology Research Center