Membrane proteins: structure, function and drug design
Stereo view of the complex showing the GGA1 VHS domain as a ribbon diagram
Membrane proteins perform important biological activities to transfer materials and information into and out of a cell. They are also important as targets for drug design. Crystallization of membrane proteins is difficult and in many cases only a very small crystals are formed. Development of high-brilliant light source and higher sensitivity detectors allows the structural analysis of micro-crystals.